Histo Calamine Lotion 60ml

Histo Calamine Lotion 60ml is a topical combination medicine containing Aloe vera, Calamine, Camphor (Cinnamomum camphora), Diphenhydramine, and Glycerol (Glycerine). It is commonly used to relieve itching, skin irritation, rashes, prickly heat, insect bites, mild allergic skin reactions, and dry skin conditions. This combination provides soothing, cooling, moisturizing, anti-itch, and skin-protective actions that help reduce redness, burning sensation, discomfort, and dryness. It offers fast symptomatic relief and improves skin comfort when used as directed by a healthcare professional.

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Written by: Syed Jommy Abbas, B. Pharma

Reviewed by: Dr. Rohit Kolhe, MBBS

Last updated on: 02-06-2026

Histo Calamine Lotion 60ml
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More About Histo Calamine Lotion 60ml

Detailed Description

Histo Calamine Lotion 60ml is a multi-action topical dermatological preparation formulated with Aloe vera, Calamine, Camphor (Cinnamomum camphora), Diphenhydramine, and Glycerol (Glycerine). This combination is commonly used for the symptomatic management of itching, skin irritation, allergic reactions, prickly heat, insect bites, mild rashes, and dry skin conditions.

Aloe vera is a natural soothing and moisturizing agent that helps calm irritated skin, reduce redness, and support skin healing. It also hydrates dry and sensitive skin.

Calamine acts as a skin protectant and anti-itch agent. It provides a cooling effect that helps relieve itching, irritation, and discomfort associated with rashes and allergies.

Camphor produces a cooling sensation on the skin and helps reduce itching, burning sensations, and mild discomfort. It also gives a refreshing effect on inflamed skin.

Diphenhydramine is an antihistamine that blocks histamine-mediated allergic reactions such as itching, redness, swelling, and irritation.

Glycerol (Glycerine) acts as a humectant and emollient. It attracts moisture to the skin and helps maintain hydration, thereby reducing dryness and roughness.

This combination provides comprehensive symptomatic relief through cooling, soothing, moisturizing, antihistaminic, and skin-protective actions. It is generally recommended for short-term use and should be used only under medical supervision.

Uses of Histo Calamine Lotion 60ml

  • Relief from itching and skin irritation
  • Management of allergic skin reactions
  • Helps relieve insect bite irritation and itching
  • Reduces redness and burning sensation
  • Provides relief in prickly heat and heat rash
  • Helps soothe dry, rough, and irritated skin
  • Used in mild contact dermatitis
  • Helps manage minor skin rashes
  • Supports the healing of irritated skin tissues
  • Provides temporary relief from minor skin allergies

Benefits of Histo Calamine Lotion 60ml

  • Histo Calamine Lotion 60ml provides quick relief from itching, irritation, redness, and burning sensations associated with minor skin conditions. The soothing and cooling ingredients improve overall skin comfort rapidly after application.
  • Aloe vera and Glycerol help moisturize dry and rough skin, improving skin softness and hydration. These ingredients also support natural skin healing.
  • Calamine and Camphor provide cooling relief from prickly heat, insect bites, and allergic skin irritation. Diphenhydramine helps reduce histamine-related itching and redness.
  • Together, these ingredients provide comprehensive soothing, moisturizing, cooling, and anti-itch effects in a single topical formulation.

Side Effects of Histo Calamine Lotion 60ml

Common side effects:
  • Mild burning or stinging sensation
  • Cooling or tingling sensation on the skin
  • Mild redness or irritation
  • Temporary dryness of the skin
  • Mild itching after application
  • Sticky feeling on the skin
Uncommon side effects:
  • Allergic skin rash
  • Swelling at the application site
  • Increased skin sensitivity
  • Mild peeling or flaking
  • Contact dermatitis
  • Skin discomfort after application
Serious side effects (seek immediate medical attention):
  • Severe allergic reactions
  • Difficulty breathing or wheezing
  • Severe redness or swelling
  • Persistent worsening of irritation
  • Severe skin rash or blistering
  • Signs of skin infection

If any side effects persist, worsen, or become severe, consult your doctor immediately.

Directions for Use

  • Use Histo Calamine Lotion 60ml exactly as prescribed by your doctor
  • Clean and dry the affected area before application
  • Apply a thin layer gently over the affected skin
  • Wash your hands before and after use
  • Avoid contact with the eyes, mouth, and open wounds
  • Do not apply excessively or cover tightly unless advised
  • Use regularly for better symptomatic relief
  • Avoid prolonged use without medical advice
  • In children, use only under adult supervision

How it works

Histo Calamine Lotion 60ml works through the combined action of multiple ingredients that provide soothing, cooling, moisturizing, and anti-itch effects.

Aloe vera helps soothe inflamed skin, reduce redness, and support skin healing. Calamine acts as a skin protectant and produces a cooling effect that relieves itching and irritation.

Camphor stimulates sensory nerve endings, creating a cooling sensation that reduces itching and burning. Diphenhydramine blocks histamine H1 receptors, which are responsible for allergic symptoms such as itching, swelling, and redness.

Glycerol (Glycerine) acts as a humectant by attracting moisture to the skin and reducing dryness. Together, these ingredients provide effective symptomatic relief in various minor skin conditions.

Safety Advice for Histo Calamine Lotion 60ml

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Allergy
Unsafe

Do not use in patients allergic to any component of the formulation. Severe allergic skin reactions may occur.

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Breastfeeding
Limited information

Use only on medical advice during breastfeeding. Avoid application near the breast area before feeding.

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Pregnancy
Caution

Use during pregnancy only if clearly needed and prescribed by a healthcare professional.

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Driving
Safe

Usually does not affect driving ability, as it is a topical medicine.

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Alcohol
Caution

Alcohol may worsen skin dryness or irritation in some individuals.

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Liver
Caution

Excessive prolonged use over large skin areas should be avoided in severe liver disease.

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Kidney
Caution

Generally safe when used as directed, but prolonged excessive use should be avoided in severe kidney disease.

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Children
Caution

Use in children only under medical supervision to avoid accidental ingestion or excessive application.

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Elderly patients
Caution

Elderly patients may have more sensitive skin and may be prone to irritation or dryness.

Quick Tips for Histo Calamine Lotion 60ml

  • Maintain proper skin hygiene during treatment
  • Avoid scratching irritated skin areas
  • Keep the affected area clean and dry
  • Avoid excessive sunlight exposure if skin is irritated
  • Use only the recommended quantity
  • Inform your doctor if symptoms persist beyond 7 days
  • Avoid applying multiple medicated creams together unless advised

Storage Advice

  • Store below 25°C in a cool and dry place
  • Protect from direct sunlight and moisture
  • Keep the container tightly closed after use
  • Keep out of reach of children
  • Do not freeze the formulation
  • Do not use after the expiry date

Drug-Food Interaction

Histo Calamine Lotion 60ml is intended for topical skin application and generally has minimal food interactions when used properly. However, certain lifestyle and dietary factors may worsen skin irritation or dryness in sensitive individuals.

Key interactions include:

  • Avoid alcohol if it worsens skin dryness or irritation
  • Maintain adequate hydration to support healthy skin
  • Avoid foods that trigger allergies if you are prone to allergic reactions
  • Follow a balanced diet to support skin healing
  • Avoid smoking and tobacco, as they may delay recovery

Interactions with Other Drugs

Histo Calamine Lotion 60ml may interact with certain topical medicines when used excessively or over large skin areas. Although systemic absorption is usually low, caution is still advised.

Important drug interactions include:

  • Other antihistamines – may increase skin sensitivity
  • Other topical anti-itch creams – may increase irritation
  • Topical steroids – excessive combined use may increase skin sensitivity
  • Local anesthetic creams – may increase numbness or irritation
  • Alcohol-containing skin products – may worsen dryness and irritation

Drug-Disease Interactions

Patients with certain skin or medical conditions should use Histo Calamine Lotion 60ml cautiously, as some ingredients may worsen underlying conditions or increase the risk of adverse reactions.

Use with caution in the following conditions:

  • Severe allergic skin disorders
  • Open wounds or severely damaged skin
  • Extensive burns
  • Severe eczema
  • Skin infections with pus formation
  • Severe liver disease
  • Sensitive skin conditions

Daily Dose

Use Histo Calamine Lotion 60ml exactly as advised by your doctor. The amount and frequency of application depend on the severity of the skin condition and the patient’s response to treatment. Apply only a thin layer over the affected area and avoid excessive use.

Overdose

Overdose of Histo Calamine Lotion 60ml is uncommon during normal topical use but may occur if large quantities are applied excessively or swallowed accidentally. Symptoms may include severe irritation, dizziness, nausea, excessive drowsiness, or allergic reactions. Seek immediate medical attention if overdose is suspected.

What If You Forget to take Histo Calamine Lotion 60ml?

If you forget to apply a dose of Histo Calamine Lotion 60ml, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your routine. Do not apply excessive amounts to compensate for the missed application.

FAQ

Fact Box

Therapeutic Class

Topical antipruritic & soothing preparation

Action Class

Skin protectant + H1 blocker + Cooling counterirritant + Moisturizer

Chemical Class

Herbal skin protectant + Antipruritic + Antihistamine + Humectant

Habit Forming

No

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