Histo Calamine Lotion 60ml is a topical combination medicine containing Aloe vera, Calamine, Camphor (Cinnamomum camphora), Diphenhydramine, and Glycerol (Glycerine). It is commonly used to relieve itching, skin irritation, rashes, prickly heat, insect bites, mild allergic skin reactions, and dry skin conditions. This combination provides soothing, cooling, moisturizing, anti-itch, and skin-protective actions that help reduce redness, burning sensation, discomfort, and dryness. It offers fast symptomatic relief and improves skin comfort when used as directed by a healthcare professional.
Written by: Syed Jommy Abbas, B. Pharma
Reviewed by: Dr. Rohit Kolhe, MBBS
Last updated on: 02-06-2026
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Histo Calamine Lotion 60ml is a topical combination medicine containing Aloe vera, Calamine, Camphor (Cinnamomum camphora), Diphenhydramine, and Glycerol (Glycerine). It is commonly used to relieve itching, skin irritation, rashes, prickly heat, insect bites, mild allergic skin reactions, and dry skin conditions. This combination provides soothing, cooling, moisturizing, anti-itch, and skin-protective actions that help reduce redness, burning sensation, discomfort, and dryness. It offers fast symptomatic relief and improves skin comfort when used as directed by a healthcare professional.
Histo Calamine Lotion 60ml is a multi-action topical dermatological preparation formulated with Aloe vera, Calamine, Camphor (Cinnamomum camphora), Diphenhydramine, and Glycerol (Glycerine). This combination is commonly used for the symptomatic management of itching, skin irritation, allergic reactions, prickly heat, insect bites, mild rashes, and dry skin conditions.
Aloe vera is a natural soothing and moisturizing agent that helps calm irritated skin, reduce redness, and support skin healing. It also hydrates dry and sensitive skin.
Calamine acts as a skin protectant and anti-itch agent. It provides a cooling effect that helps relieve itching, irritation, and discomfort associated with rashes and allergies.
Camphor produces a cooling sensation on the skin and helps reduce itching, burning sensations, and mild discomfort. It also gives a refreshing effect on inflamed skin.
Diphenhydramine is an antihistamine that blocks histamine-mediated allergic reactions such as itching, redness, swelling, and irritation.
Glycerol (Glycerine) acts as a humectant and emollient. It attracts moisture to the skin and helps maintain hydration, thereby reducing dryness and roughness.
This combination provides comprehensive symptomatic relief through cooling, soothing, moisturizing, antihistaminic, and skin-protective actions. It is generally recommended for short-term use and should be used only under medical supervision.
If any side effects persist, worsen, or become severe, consult your doctor immediately.
Histo Calamine Lotion 60ml works through the combined action of multiple ingredients that provide soothing, cooling, moisturizing, and anti-itch effects.
Aloe vera helps soothe inflamed skin, reduce redness, and support skin healing. Calamine acts as a skin protectant and produces a cooling effect that relieves itching and irritation.
Camphor stimulates sensory nerve endings, creating a cooling sensation that reduces itching and burning. Diphenhydramine blocks histamine H1 receptors, which are responsible for allergic symptoms such as itching, swelling, and redness.
Glycerol (Glycerine) acts as a humectant by attracting moisture to the skin and reducing dryness. Together, these ingredients provide effective symptomatic relief in various minor skin conditions.
Histo Calamine Lotion 60ml is intended for topical skin application and generally has minimal food interactions when used properly. However, certain lifestyle and dietary factors may worsen skin irritation or dryness in sensitive individuals.
Key interactions include:
Histo Calamine Lotion 60ml may interact with certain topical medicines when used excessively or over large skin areas. Although systemic absorption is usually low, caution is still advised.
Important drug interactions include:
Patients with certain skin or medical conditions should use Histo Calamine Lotion 60ml cautiously, as some ingredients may worsen underlying conditions or increase the risk of adverse reactions.
Use with caution in the following conditions:
Use Histo Calamine Lotion 60ml exactly as advised by your doctor. The amount and frequency of application depend on the severity of the skin condition and the patient’s response to treatment. Apply only a thin layer over the affected area and avoid excessive use.
Overdose of Histo Calamine Lotion 60ml is uncommon during normal topical use but may occur if large quantities are applied excessively or swallowed accidentally. Symptoms may include severe irritation, dizziness, nausea, excessive drowsiness, or allergic reactions. Seek immediate medical attention if overdose is suspected.
If you forget to apply a dose of Histo Calamine Lotion 60ml, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your routine. Do not apply excessive amounts to compensate for the missed application.
Therapeutic Class
Topical antipruritic & soothing preparation
Action Class
Skin protectant + H1 blocker + Cooling counterirritant + Moisturizer
Chemical Class
Herbal skin protectant + Antipruritic + Antihistamine + Humectant
Habit Forming
No
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