Can I use this Estradiol 2mg tablet for vaginal dryness and discomfort during intimacy?

Estradiol is indeed used to help with vaginal dryness, particularly around menopause, since it addresses the hormonal changes behind it. Depending on your situation, though, your doctor might suggest a local vaginal preparation instead of an oral tablet, since that often targets the symptom more directly with fewer systemic effects. It's worth discussing your specific case with a gynecologist so you get the form that suits you best.